Helminth infection inflammation. Veterinary Neuropathology: Essentials of Theory and Practice - intellicig.ro
Comentarii The type 2 immune response that develops during infectious disease has undergone major paradigm shifts in the helminth infection inflammation several years as new cell types helminth infection inflammation pathways have been identified. It is now clear that the type 2 immune response, characterized by elevations in specific cytokines, including IL-4, IL-5 and IL, is associated with helminth infections in both humans and mice.
This response is complex and includes effector helminth infection inflammation that mediate resistance, contributing to expulsion and in some cases destruction, of the parasite. Helminth infection inflammation just as importantly, the type 2 immune response can also mediate tolerance mechanisms, which can mitigate tissue injury as these large multicellular parasites transit through vital organs.
The tolerance mechanisms include both tissue repair and immune regulatory effects.
These latter aspects of the helminth-induced type 2 immune response are increasingly recognized as a potential resource that can be helminth infection inflammation for the development of novel immunotherapies that may enhance wound healing, control of autoimmune and inflammatory diseases and regulation of metabolic homeostasis.
In this book, leading researchers in this exciting and dynamic field discuss the latest findings and emerging concepts, providing an intellectual framework that can be used as a basis for new discoveries and potentially new treatments for diseases associated with inflammation.
An aparitie: 26 Dec Autor: William C.