Sarcoma cancer of the soft tissue, REVIEW-URI

It has been reported a low incidence in the head and neck. Magnetic resonance imaging was useful in preoperative evaluation.

The treatment consisted in radical resection, and the histological analysis completed the diagnosis. The postoperative management consisted in a combination of chemotherapy for systemic control and irradiation for local control.

Specificații

A very few cases of cervical tumors were reported. Radical resection followed by radio-chemotherapy has good results in the treatment of this rare tumor.

Sarcomul Ewing extrascheletal este o tumoră rară, de origine mezenchimală, similară din punct de ve­de­re histologic cu osteosarcomul Ewing. Este o tumoră rar întâlnită la nivelul capului și gâtului.

4. Recurrent respiratory papillomatosis avastin

5. Макс, сердце которого колотилось настолько отчаянно, что он ощущал пульс даже челюстью, качнул головой и сказал: "Не понимаю".

6. Cheloo toate femeile
7. Cancer colon simptome si cauze

Autorii pre­zin­tă un caz de sarcom Ewing extrascheletal sub forma unei tumori laterocervicale stângi situate posterior de muș­chiul sternocleidomastoidian. Examenul RMN a fost util în evaluarea preoperatorie.

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• Sarcom Ewing extrascheletal sub forma unei mase tumorale la nivelul gâtului - prezentare de caz

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Tratamentul a constat în excizia ra­di­cală a tumorii laterocervicale, urmată de examen his­to­pa­to­logic. Postoperator s-au efectuat chimioterapie pen­tru controlul sistemic și radioterapie pentru controlul lo­­cal.

А потом придется запасаться заново". Жанна и Алиенора отсутствовали уже сорок восемь часов. Последние две недели пребывания Николь в каморке, вырытой под сараем Макса Паккетта, один из двух роботов постоянно разделял ее компанию.

Говорить с ними было все равно, что с самим Ричардом, - во всяком случае, поначалу, пока Николь еще не успела истощить запас тем, хранившихся в памяти этих маленьких "Пожалуй, эти дамы - самые великие творения Ричарда, - сказала себе Николь, опускаясь в кресло. - Должно быть, он потратил не один месяц, чтобы изготовить их".

Sarcomul Ewing ex­­trascheletal este o tumoră rară, cu evoluție agresivă. În li­te­ratură au fost raportate puține cazuri de sarcoame Ewing ex­trascheletale prezentate sub forma unor tumori la­te­ro­cervicale.

Excizia radicală urmată de radiochimioterapie are cele mai bune rezultate în tratamentul acestor tumori. It was first recognized by Tefft et al.

Extraskeletal Ewing’s sarcoma presenting as a neck mass - case report

According to Chao et al. In head and neck, EES is usually identified in nasal or oral cavities, sinuses or soft tissues sarcoma cancer of the soft tissue. EES is characterized by an aggressive course and high rate of recurrences.

The treatment consists in a combination of surgery, radiotherapy and chemotherapy. Case report A year-old female was admitted in ENT Department with a 2-month history of painless posterior left laterocervical mass with rapid evolution Figure 1.

Figure 1.

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Figure 2. MRI transversal plane The videofibroscopy of rhinopharynx, hypopharynx and larynx was normal.

Proper classification and staging is essential for the physician to assign proper treatment, evaluate results of management and clinical trials, and to serve as the standard for local, regional and international reporting on cancer incidence and outcome.

The MRI showed a posterior laterocervical solid mass, with a maximum diameter of 8 cm Figure 2 and Figure 3. Figure 3. MRI coronal plane Figure 4.

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Intraoperative image after complete removal of the tumor Figure 5. The patient at 2 months after surgery - local recurrence The patient underwent surgical excision followed by histopathological exam Figure 4.

The patient underwent 6 chemotherapy cycles with vincristine, doxorubicin and cyclophosphamide, followed by external radiotherapy.

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Figure 6. PET-CT scan 2 months after surgery - sagittal view At 10 months after initial diagnosis, the patient presented with incomplete resolution of the tumor Figure 8severe radiomucositis grade 4 WHO and was admitted in the oncology department. Figure 8. EES in head and neck region must be differentiated from lymphoma, rhabdomyosarcoma, poorly differentiated salivary gland tumors, olfactory neuroblastoma, undifferentiated nasopharyngeal carcinoma and melanoma.

Case particularities The localization of EES in the neck is very rare. Comorbidities - immunosuppression caused by chronic use of prednisolone could be an etiologic factor. Delay of the radiotherapy after surgery 2 months caused tumor recurrence, EES being a very aggressive type of tumor.

Sarcom Ewing extrascheletal sub forma unei mase tumorale la nivelul gâtului - prezentare de caz

Bibliografie 1. Head Neck Pathol. Hum Pathol. Eur J Cancer Clin Oncol.

J Laryngol Otol. Windfuhr JP. Primitive neuroectodermal tumor of the head and neck: incidence, diagnosis, sarcoma cancer of the soft tissue management.

Ann Otol Rhinol Laryngol.