[Myometrial invasion as a prognostic factor in endometrial adenocarcinoma].

Endometrial cancer histology

Utilitatea imunohistochimiei în diagnosticul carcinomului ovarian

Several previous studies have identified an association between endometriosis and the development of ovarian carcinomas. This study aims to follow-up the prevalence of endometriosis and the histological features in ovarian tumors. Materials and endometrial cancer histology. The study group included 50 patients endometrial cancer histology the County Emergency Hospital of Galaţi diagnosed with different histological types of ovarian tumors of endometrial cancer histology surface epithelium during the period The cases were reviewed in order to highlight the presence of endometriosis and the different histopathological changes.

[Myometrial invasion as a prognostic factor in endometrial adenocarcinoma].

The average endometrial cancer histology of patients in the group with endometriosis associated with ovarian tumors was From the seven cases of tumors associated with endometriosis, two presented areas with atypia, considered premalignant lesions. Based on data obtained, we can conclude that endometriosis with atypia can be a precursor to the occurrence endometrial cancer histology type I ovarian carcinomas.

Keywords endometriosis, ovarian cancer, atypical endometriosis, premalignant lesion Rezumat Introducere. Mai multe studii anterioare au identificat o asociere între endometrioză şi dezvoltarea carcinoamelor ovariene.

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Acest studiu urmăreşte prevalenţa endometriozei şi caracteristicile histologice în tumorile ovariene. Materiale şi metodă. În lotul de studiu au fost incluse 50 de paciente diagnosticate cu diferite tipuri histologice de tumori ovariene ale epiteliului de suprafaţă în perioada la Spitalul Judeţean de Urgenţă din Galaţi.

endometrial cancer histology chimioterapia pt cancerul pulmonar cu celule mici metastatic

Cazurile au fost reanalizate în vederea evidenţierii prezenţei endometriozei, precum şi a diferitelor modificări histopatologice ale acestora. Vârsta medie a pacientelor a fost 59,4±11,35 ani în lotul pacientelor care au prezentat endometrioză asociată şi 59,5±13,4 ani în lotul pacientelor care au prezentat doar tumori ovariene.

  • Particularităţile morfologice şi ultrasonografice ale pacientelor afectate de cancerul endometrial
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  • [Myometrial invasion as a prognostic factor in endometrial adenocarcinoma].
  • Uterine (Endometrial) Cancer: Prediction Tools | Memorial Sloan Kettering Cancer Center
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Din cele şapte cazuri de endometrioză, în două cazuri au fost evidenţiate zone cu atipii, considerate leziuni endometrial cancer histology. Identificarea endometriozei cu atipii la cele două cazuri — unul diagnosticat cu carcinom cu celule clare, iar celălalt cu carcinom endometrial, ambele incluse în tipul I de cancer ovarian — demonstrează faptul că endometrioza cu atipii poate fi un precursor în apariţia carcinoamelor ovariene de tip I.

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Endometriosis is a gynecological condition, being characterized from endometrial cancer histology histopathological point of view by the presence of glandular structures at the level of the endometrium and stroma in ectopic locations, such as ovary, pelvis, bladder, Fallopian tube, ovary representing endometrial cancer histology most common location 4,5.

The literature comprises multiple studies highlighting the link between the presence of endometriosis and its malignant transformation in the ovary, although other studies have not identified associations between these two 6,7. It is estimated that the risk of malignant transformation of endometriosis is comprised between 0.

The purpose of this paper is to quantify the in­ci­dence of different histological types of ovarian tumors and to demonstrate the clinical importance of an effective screening program, considering the paucisymptomatic na­ture of this pathology. The incidence of ovarian epithelial tumors varied across age groups, our study group including women aged endometrial cancer histology 34 and 64 years old.

Endometriosis with atypia is described as a preneoplastic endometrial cancer histology and is considered an intermediate pathway for the development of ovarian carcinoma 3. InSampson described for the first time the implications of endometriosis in neoplastic lesions by establishing several important criteria: the presence of endometriosis and the tumor in the same ovary, a similar histological pattern, the exclusion of the presence of tumor metastasis from other locations 8.

Utilitatea imunohistochimiei în diagnosticul carcinomului ovarian

InScott added one more criterion: highlighting the continuity between the benign and the malignant epithelium 9.

Atypia from endometriosis was endometrial cancer histology as a preneoplastic lesion between endometriosis and ovarian cancer, as endometrial cancer histology cancer histology refers to two major histological changes: cytological atypia and architectural atypia known as hyperplasia Cytological atypia is highlighted in the epithelium of an endometrial cyst, while the hyperplasia resembles endometrial cancer histology the hyperplasia present in the endometrium simple or complex with or without atypia Materials and method The study comprises patients of the Emergency County Hospital of Galaţi diagnosed with papillomatous mass meaning carcinoma during the period January — December The histopathological results were analyzed retrospectively to identify the presence of endometriosis.

endometrial cancer histology

A number of diagnosed cases and ovarian tumors were analyzed in order to identify the presence or absence of endometriosis, as well as the relationship between these two, based on the criteria listed before. In this study, we included and evaluated a number of 50 patients diagnosed with epithelial ovarian carcinomas, but also with borderline ovarian tumors.

GHID din 4 decembrie privind cancerul de endometru Anexa nr.

The present study aims to identify the presence of endometriosis outbreaks with or without cytological or architectural atypia hyperplasia.

Each case was evaluated from a histopathological point of view.

The number of paraffin blocks varied depending on the surgical pieces, being between 4 and 12 blocks, the slides resulting from the section of these blocks being processed and colored using the classic hematoxylin and eosin coloration. The following clinical and pathological data of the patients were taken into account: age, menopausal status, tumor histological type, tumor grading at the time of ovarian diagnosis.

The staging was made retrospectively according to the system of the International Federation of Gynecology and Obstetrics FIGO after cases have been analyzed.

endometrial cancer histology

Endometrial cancer histology histological classification of ovarian carcinomas was based on the classification WHO of ovarian tumors. Results The histopathological evaluation performed on the group of 50 patients during the period has the following results: 45 endometrial cancer histology were diagnosed with malignant tumors, 5 cases endometrial cancer histology borderline tumors.

Incidence of endometriosis and atypical endometriosis in epithelial ovarian tumors

Figure 1. Figure 2.

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From the seven patients with endometriosis, None endometrial cancer histology the cases of borderline mucinous tumors, mucinous carcinoma, and undifferentiated carcinoma presented associated endometriosis outbreaks Table 1. Table 1.

Incidenţa endometriozei şi a endometriozei atipice în cazul tumorilor ovariene epiteliale

The presence of endometriosis in the appendages was Two of the seven cases in which the areas of endometriosis were visualized presented also endometriosis with atypia one case of complex hyperplasia, and the other with cytological atypia in the wall of an endometrial cyst.

In our study, the average age at the moment of diagnosis was One of the studies reported in the literature identified an average age of The association endometrial cancer histology endometriosis and ovar­ian cancer is reported in the expert studies under two categories. In all other cases, the ovarian tumor literally coexisted with endometrial cancer histology without the identification of a transition 13,