Hodgkin cancer symptoms
The signs and symptoms can be easily confused with symptoms associated to pregnancy. Although the lymph node biopsy provides the certain diagnosis, all the other investigations must be performed.
The treatment should be adjusted to each case. Astfel, managementul acestei patologii reprezintă o provocare, mai ales când afectează adolescente.
Semnele şi simptomele pot fi cu uşurinţă confundate cu manifestări ale sarcinii. Deşi biopsia ganglionară furnizează diagnosticul de certitudine, este necesară o investigare paraclinică suplimentară. Tratamentul trebuie ajustat fiecărui caz. These abnormal lymphocytes — lymphoma cells — form tumors in lymph nodes or in other parts of the body like spleen, liver or bone marrow 1.
HL is one of the most common lymphomas diagnosed during pregnancy, especially because the peak incidence of this disease coincides with female reproductive age 2.
HL is diagnosed in approximately to pregnancies 3. Depending on the histological subtype, the incidence of HL varies in different percentages all over the world: in developed countries it predominates the nodular sclerosis HL accounting in young adults; in economically disadvantaged areas it is more frequent a mixed cellularity HL accounting in children and older adults Pregnant patients with HL have the same signs and symptoms as non-pregnant patients with HL.
The particularity of the diagnosis in pregnancy resides in the fact that some signs and symptoms caused by HL fatigue, shortness of breath, anemia, thrombocytopenia overlap with common signs and symptoms seen during pregnancy, so it is very possible to omit the correct diagnosis from the beginning and this can cause a delay of diagnosis and precious hodgkin cancer symptoms is lost A relatively common finding is eosinophilia that may be determined by the production of chemokines, such as interleukin-5 and eotaxin 8,11, Staging during pregnancy The initial hodgkin cancer symptoms evaluation of pregnant patients suspected for HL should include: History and physical examination.
Laboratory studies: complete blood hodgkin cancer symptoms, erythrocyte sedimentation rate ESR, which hodgkin cancer symptoms often significantly elevated during normal hodgkin cancer symptoms creatinine concentration, serum liver enzymes, alkaline phosphatase and HIV serology. Evaluation of the intraabdominal disease with magnetic resonance imaging MRIcomputed tomography or ultrasound Bone marrow biopsy.
During pregnancy gallium scan, PET scan or bone scan are not indicated in order to establish the diagnose of HL The management of HL during pregnancy requires good communication between the haemato-oncologist, obstetrician, nurse specialists, midwives and neonatologists.
Traducere "Hodgkin lymphoma" în română
Although the goal of treatment should remain curative, there still exists some debate regarding the timing of chemotherapy, the curative nature of treatment and the timing of delivery She was gravida 1, para 1. The patient had insignificant personal pathological history.
Hodgkin cancer symptoms her parents, we nasal papilloma surgery out that she was the fourth child, with a normal somatic and papillomas size development. She was vaccinated according to the National Program of Vaccination. She had a body mass hodgkin cancer symptoms BMI of The patient began investigating her pregnancy at weeks of amenorrhea.
Until 19 weeks of pregnancy, there were no pathological problems, except for a chronic anemia, treated with oral iron. At weeks of pregnancy, the previous symptoms were aggravated and she presented to her physician with productive cough, dyspnea and bilateral cervical lymphadenopathy.
At the pulmonary exam, bronchi rales were detected, therefore she was directed to hodgkin cancer symptoms Emergency Room of the Emergency Clinical Hospital of Târgu-Mureş.
An ultrasound of soft tissue was performed, which indicated multiple lymphadenopathy — bilateral cervical, bilateral supraclavicular, between 5 mm and 4 cm. The blood samples indicated an important inflammatory syndrome, chronic anemia HGB 7.
An MRI was performed and revealed an adenopathyc mediastinal block with large vessels imbedded, with a mass effect on the trachea and esophagus and compressive effect on the superior vena cava and brachiocephalic trunks, confluent adenopathy mass retro and supraclavicular bilateral, axillary bilateral and middle and lower carotid-jugular.
A thoracic examination was performed which revealed non-homogeneous pulmonary condensation in the right costo-diaphragmatic sinus without tumor hodgkin cancer symptoms. Also, the intradermal test for Koch bacillus BK was effectuated, and sputum examination for BK which was negative.
During this hospitalization, the previous signs and symptoms were persistent. In addition, a thoracic examination was conducted hodgkin cancer symptoms revealed a mediastinal compression syndrome.
A bone marrow cytology was performed — normal values were observed. Corticotherapy was initiated immediately: 8 mg of dexamethasone during the first day, 12 mg per day for the next 10 days, with progressive dose reduction. The initial evolution was clinically favorable, with diminishing adenopathy. The evolution was good for six days. In the seventh day, the right cervical and hodgkin cancer symptoms adenopathy began to increase in size.
A second ABVD chemotherapy series was initiated, with a good clinical tolerance. During the hospitalization, five blood transfusions were performed. The gynecological examination was conducted weekly at the Bucharest University Emergency Hospital and a second-trimester morphology was performed, with normal results, excepting an amniotic fluid index at the inferior limit of the normal range.
Ante-, intra- and postpartum management of a pregnant adolescent diagnosed with Hodgkin’s lymphoma
The obstetrical examination was unremarkable. The hodgkin cancer symptoms examination was normal, except for an amniotic fluid index at the inferior limit of normal. The lab tests indicated chronic anemia HGB 9. The samples for thrombophilia were analyzed, with no notable modifications. The chest radiography revealed a mediastinal mass Figure 1. A multidisciplinary team participated in the management of the patient obstetrician, neonatologist, pediatrician, ENT specialist, hematologist and an intensive care unit specialist.
Tocolytic treatment and corticotherapy were initiated. The evolution of both the mother and newborn was favorable.
How Lymphoma Develops
Figure 1. Chest radiography.