Human papillomavirus 52 positive squamous cell carcinoma of the conjunctiva

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Department of Ophthalmology, Grigore T. E-mail: moc.

Acesta sta la baza majoritatii neoplaziilor cervicale, dar si intr-un procent mai scazut al celor vulvare, anale si hpv skin doctor zona gatului. Virusul Papilloma uman se infiltreaza in mucoase si in piele, transmitandu-se pe cale sexulala exclusiv, de multe ori fara ca partenerii sa fie instiintati de existenta lui. Aceasta infectie nu prezinta simptomatologie asociata. Exista aproximativ de tipuri si subtipuri de HPV diferite genetic. Distingem dintre tipurile de virus HPV LR 6 si 11 stau la baza condiloamelor si papiloamelor genitale.

We report the detection of HPV 52 in a sample taken from a year-old patient with squamous cell carcinoma of the conjunctiva of the left eye.

The method used for the detection of HPV was real time polymerase chain reaction. The evolution was favorable after surgical removal of the tumor and the patient was explained that long-term follow-up is essential to avoid recurrence.

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Keywords: Conjunctiva, eye, human papillomavirus 52, real time polymerase chain hpv skin doctor, squamous cell carcinoma Human papillomavirus HPV infection is strongly associated with anogenital tumors cervix, penis, vulva, anushead and neck cancers oral cavity, hpv skin doctor, larynxand nonmelanoma skin cancers squamous and basal cell carcinoma.

The association between HPV infection and eye tumors is little explored territory.

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Di Girolamo brings forward a two-hit theory that explains cancerogenesis in OSSN: The first hit is mediated by ultraviolet radiation exposure that causes genetic alteration and the second hit is mediated by HPV infection in the susceptible cells. Case Report We present a unique case of squamous cell carcinoma of the conjunctiva hpv skin doctor and treated in June The year-old patient presented at the Ophthalmology Department for mild stinging sensation and redness in the left eye for almost 1-year and hpv skin doctor half.

He has been treated for the last 2 months with dexamethasone eye drops for scleritis by another ophthalmologist.

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The patient admits being a heavy smoker hpv skin doctor almost 30 years and that in his free time he practices agriculture without using sunglasses. All hpv skin doctor ophthalmological findings were normal.

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Conjunctival culture was performed before surgery, and no bacterial infection was found. The CT scan of the head and neck showed no signs of tumor invasion of the orbit or the lymph nodes.

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The limbic lesion was removed surgically with 2 mm margin of normal tissue and diathermy of the adjacent sclera was done. At the end, the remaining temporal defect was restored using a supero-nasal conjunctiva graft fixed in position with interrupted and hpv skin doctor The excised tumor was cut into 2 fragments: One for pathology preserved in formalin and one for HPV genotyping preserved in Cobas polymerase chain reaction PCR hpv skin doctor and refrigerated at 4°C until processing.

HPV is a DNA virus with tropism for skin and mucous membranes; up to date, more than types have beeen identified.

Histopathology exam showed a moderate differentiated keratinized squamous cell carcinoma of the conjunctiva without koilocytosis [Figs.